Research Article
Hot-Stage Microscopy for Determination of API Particles in a Formulated Tablet
Table 1
List of used APIs, excipients, their melting points, and composition of mixture and tablets.
| | Tadalafil | Meloxicam | Calcium carbonate | Methocel | Lactose monohydrate | Avicel PH102 | Colloidal silicon dioxide | Crospovidone | Magnesium stearate | Povidone |
| Melting point [°C] | 286–295 | 242–250 | 825 | 225–230 | 214–216 | 260–275 | 1600 | 150–180 | 117–150 | 150–180 | Mixture 1 | ● | | | ● | | | | | | | TFL Tbl 1 | ● | | ● | | ● | | ● | | ● | | ME Tbl 1 | | ● | | | ● | ● | ● | ● | ● | | ME Tbl 2 | | ● | | | ● | ● | ● | ● | ● | ● |
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