High-Level Antimicrobial Efficacy of Representative Mediterranean Natural Plant Extracts against Oral Microorganisms
Table 2
Antimicrobial activity in mg mL−1 of four mastic gum extracts.
Mastic gum
Sample
Total mastic extract
DMSO (%)
c/mg mL−1
MIC*
MBC**
MIC
MBC
Streptococcus mutans DSM 20523
NA
NA
5.00
40.00
Streptococcus sobrinus DSM 20381
NA
NA
10.00
20.00
Streptococcus oralis ATCC 35037
2.50
5.00
10.00
20.00
Enterococcus faecalis ATCC 29212
NA
NA
10.00
80.00
Candida albicans DSM 1386
NA
NA
10.00
10.00
Escherichia coli ATCC 25922
NA
NA
10.00
10.00
Staphylococcus aureus ATCC 25923
2.50
5.00
20.00
80.00
Porphyromonas gingivalis W381
0.02
0.07
10.00
20.00
Prevotella intermedia ATCC 25611
0.07
0.30
2.50
5.00
Fusobacterium nucleatum ATCC 25586
2.50
2.50
10.00
20.00
Parvimonas micra ATCC 23195
0.60
0.60
2.50
10.00
NA: no activity observed; MIC or MBC was measured at 10.00 mg mL−1. MIC: extract concentration at which a three-log reduction (99.9%) of the bacterial growth was induced. MBC: extract concentration at which a three-log reduction (99.99%) of the bacterial growth was induced.
