Adenosine Amine Congener as a Cochlear Rescue Agent

Figure 4

Pharmacokinetic properties of ADAC in plasma after administration through the femoral vein (400 μg/kg, 1 mL/min). Data are expressed as mean ± SEM ( per time point). Pharmacokinetic properties were calculated using an Excel plugin PKSolver [24]. , extrapolated maximum concentration; , half-life; , elimination constant; , the integral area under the curve, measuring the overall amount of ADAC in the compartment.