Polymorphisms in the RANK/RANKL Genes and Their Effect on Bone Specific Prognosis in Breast Cancer Patients

Table 2

Genotype and allele distribution.

SNP	Chrom.^1	Position	Alleles^2	MAF^3 (%)	Homozygous common^4	Heterozygous^4	Homozygous rare^4
rs1054016 (RANKL)	13	43182002	G/T	42.2	427 (34.1)	592 (47.3)	232 (18.5)
rs1805034 (RANK)	18	60027241	T/C	47.8	337 (26.9)	632 (50.5)	282 (22.5)
rs35211496 (RANK)	18	60021761	C/T	17.3	861 (68.8)	347 (27.7)	43 (3.4)

1Chromosome; ²major/minor allele, based on the forward strand and minor allele frequency; ³minor allele frequency; ⁴frequency, percentage in brackets.