High Expression of Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 Predicts Poor Prognosis in Head and Neck Squamous Cell Carcinoma

Table 1

LETM1 protein expression in HNSCC and normal squamous epithelia.

Diagnosis	Number of cases	LETM1 expression				Positive rate (%)	Strongly positive; rate (%)
		−	+	++	+++
SCC	176	34	27	73	42	80.7%**	65.3%**
Adjacent non-tumor	72	35	19	10	8	51.4%**	25.0%*
Normal epithelia	45	35	7	3	0	22.2%	6.7%

SCC: squamous cell carcinoma.
Positive rate: percentage of positive cases with +, ++, and +++ staining score. Strongly positive rate: (high-level expression) percentage of positive cases with ++ and +++ staining score.
^∗𝑃<0.05 and ^∗∗𝑃<0.01 compared with normal epithelia.