Review Article

Potential Biomarkers and Their Applications for Rapid and Reliable Detection of Malaria

Figure 3

Detection of pLDH by electrochemical impedance spectroscopy. The aptamer is shown as a chain of different coloured circles, representing the four bases A, T, G, and C. Capture of pLDH by aptamer results in a decrease in electron transfer to electrode. The pLDH aptasensor can distinguish between malaria positive blood samples of two major species (P. vivax and P. falciparum) and has a detection limit of 1 pM. [115].
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