Review Article

Potential Biomarkers and Their Applications for Rapid and Reliable Detection of Malaria

Table 3

Comparison of evaluation reports of various RDTs done in the recent years.

Dipstick Standard Population Sensitivity
(%)
Specificity
(%)
Reference

CareStart (Access Bio, Princeton, NJ, USA) GTTS* Southwestern Uganda 95.691.5 [154]
Vistapan (Mitra, New Delhi, India)91.989.6
Parabank ( Orchid/Zephyr, Goa, India)84.794.3
Paracheck pf (Orchid/Zephyr, Goa, India)9487.3
Optimal-IT (DiaMed, Cressier, Switzerland)GTS**Gabon
Children under
11 years
9497 [155]
Acon (Acon Labs, San Diego, CA, USA)9490
PALUTOP+4 (ALL.DIAG, Strasbourg, France)GTTS* and PCRMadagascar95.497.1 [156]
Optimal-IT (DiaMed, Cressier, Switzerland)75.899.0
ParaHIT f test (Span Diagnostic Ltd., Surat, India)GTTS* and PCRTanzania69.2100 [157]
Malaria PfGTTS*Uganda9872[135]
Paracheck Pf (Orchid Biomedical Systems, Goa, India)GTTS*Kenya91.796.7[158]
Malar-Check_Pf testGTS**Brazil97.4%88.5%[159]
Makromed Dipstick AssayPCRCanada97.0%96.0%[160]
ParaSight-F (Becton Dickinson, USA)Thin blood smears and Quantitative
Buffy Coat malaria test
France94%99%[161]
ParaSight-F (Becton Dickinson, USA)MicroscopyIquitos, Peru, and Maesod, Thailand95%86%[162]
Paracheck Pf (Orchid Biomedical Systems)MicroscopyIndia93%84%[163]
ParaHIT-f (Span Diagnostics)GTS**Tanzania90.7%73.5%[164]
ParaHIT-f (Span Diagnostics)MicroscopyIndia87.5%97%[163]

Giemsa thick smear.
*Giemsa thick and thin smear.