A RXR Ligand 6-OH-11-O-Hydroxyphenanthrene with Antitumour Properties Enhances (−)-Epigallocatechin-3-gallate Activity in Three Human Breast Carcinoma Cell Lines
Figure 3
RXR, Hoxa1, and GCNF expression. RXRα and RXRβ γ qRT-PCR ((a) and (b)): MCF-7, MCF-7TAM, and MDA-MB-231 cells responded to treatments increasing RXRα and/or β γ with the exception of MDA-MB-231 cells, which downregulated RXRβ γ expression after IIF and EGCG + IIF treatments. (c) RXRγ protein Western blot analysis: RXRγ protein detection by Western blot. ((d) and (e)) RXR responder gene expression. ; . n.d.: not detected as significant.