Mechanotransduction in Musculoskeletal Tissue Regeneration: Effects of Fluid Flow, Loading, and Cellular-Molecular Pathways

Figure 2

Representative 3D μCT images of trabecular bone in distal femur. Graphs show mean ± SD values for bone volume fraction (BV/TV, %), connectivity density (Conn.D, 1/), trabecular number (Tb.N, 1/mm), and separation (Tb.Sp, mm). MS at 50 Hz produced a significant change in all indices, compared to HLS. versus baseline; versus age-matched; versus HLS and 1 Hz MS; versus HLS and 1 Hz MS; versus HLS and 1 Hz MS.