Research Article

Benchmarking B-Cell Epitope Prediction with Quantitative Dose-Response Data on Antipeptide Antibodies: Towards Novel Pharmaceutical Product Development

Figure 1

IEDB B-cell search interface (URL http://www.immuneepitope.org/advancedQueryBcell.php/) for retrieval of B-cell assay records. Unless otherwise specified, default options are set. Under “1st Immunogen” (with radio/check button checked for “MUST be present in search results”), “Epitope relation” and “Type” are set to “Epitope” and “Linear peptide,” respectively. Inset with red border contains screenshot of Assay Finder pop-up window (activated by clicking the Assay Finder button located behind inset on “Assay” line, just below “Quantitative measurement” line under “B Cell Assay” heading visible to the left of inset), with “antibody dependent biological activity” selected using the B cell Assay Tree (shown in right panel of inset).
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