Clinical Study

Expression of IMPDH mRNA after Mycophenolate Administration in Male Volunteers

Figure 1

Plasma total MPA concentrations ((a) and (b)), IMPDH1 mRNA expressions ((c) and (d)), and IMPDH2 mRNA expressions ((e) and (f)) in the first week and the second week, respectively, over 10 h after the administration of MMF to the six volunteers. Black arrow means the administration of MMF. The -axis in mRNA expression graph is arbitrary unit, showing the ratio of IMPDH mRNA expression to ACTB (reference gene) mRNA expression.
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(a)
870209.fig.001b
(b)
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(c)
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(d)
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(e)
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(f)