Research Article

A Proxy Outcome Approach for Causal Effect in Observational Studies: A Simulation Study

Table 4

Empirical application, predicting adults’ health status (outcome of interest) and their children’s health status (proxy outcome) by alcohol use (proxy outcome).

Have undesirable health status in adultsHave undesirable health status in children
Odds Ratio95% confidence intervalOdds ratio95% confidence interval

Parents’ drinking behaviour
 Lifetime abstainers1.00Reference1.00Reference
 Current light drinkers0.540.420.690.600.500.71