New Progress in Angiogenesis Therapy of Cardiovascular Disease by Ultrasound Targeted Microbubble Destruction
Figure 6
Representative images of pericyte coverage from nonischemic and schematic adductor muscle in respective therapy group at 8 weeks after ligation, von willebrand factor (vWF)-endothelial cells (red), and TOPRO-3-nuclei (blue). (a) NG2-pericyte coverage, (green). Scale bar = 100 μm. (b) Platelet-derived growth factor receptor (PDGFR)-beta-pericyte coverage, (green). Scale bar = 20 μm, colocalization of vWF and either NG2 or PDGFR-beta (yellow). There were the greatest pericytes expressing NG-2 (a) and PDGFR-beta (b) in VEGF + Ang-1 late groups. Adapted from [41].