7-Tesla Magnetic Resonance Imaging Precisely and Noninvasively Reflects Inflammation and Remodeling of the Skeletal Muscle in a Mouse Model of Antisynthetase Syndrome
Figure 3
T2 and DTI MRI mapping reflect independent inflammatory events in acutely injured muscles. Representative T2-weighted images before (time 0) and at various times (1, 5, or 10 days) after intramuscular CTX injection ((a) upper images). Results are compatible with those obtained at the same time points by histopathology in selected animals ((a) lower panels, H&E). The graphs show the dynamic trends of T2-rt ((b) y-axis) and F.A. ((c) y-axis) in the longitudinal study of damaged (CTX) and sham-treated mice before and at various times after treatment (x-axis, days). ; statistically different from sham-treated mice; .
