Research Article
Variations in KIR Genes: A Study in HIV-1 Serodiscordant Couples
Table 1
Demographic and clinical characteristics of enrolled HIV-1 discordant couples (
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| | Variables | |
| | Cohort period | 2010–2013 | | Number of discordant couples enrolled | 47 | | Male:female ratio | 30 : 17 | | Age of seropositives (HSPs) (mean ± SD) | yrs | | Males () | yrs | | Females () | yrs | | Age of exposed seronegatives (HSNs) | yrs | | Males () | yrs | | Females () | yrs | | Opportunistic/coinfections | 12 (25.5%) TB (M: 10; F: 2) | | 3 (6.03%) Herpes zoster (M: 1; F: 2) | | 2 (4.2%) Syphilis (M: 2) | | Route of HIV transmission | | | Heterosexual | 28 (59.6%) | | Blood transfusion | 3 (6.4%) | | Infected needle prick | 3 (6.4%) | | Not known | 13 (27.7%) | | ART given after enrollment | 18 (38.3%) (M: 11; F: 7) | | Not on ART | 29 (61.7%) (M: 19; F: 10) | | Duration of exposure before enrollment (mean ± SD) | months | | Duration of exposure after enrollment (mean ± SD) | months | | Median HIV-1 viral load () | 22137 RNA copies/mL (4.34 ) | UD: 6, <1000: 11, 1001–9999: 10,
10,000–50,000: 8, 50,001–1,10,000: 2, >1,10,000: 10 | | UD viral load in HSPs after ART initiation | | | CD4 count (median ± SD) | cells/L | | HSPs with <200 CD4 count | 8 (17%) |
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TB: tuberculosis, ART: antiretroviral therapy, RNA: ribonucleic acid, M: male, F: female, UD: undetectable.
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