Research Article
Variations in KIR Genes: A Study in HIV-1 Serodiscordant Couples
Table 5
KIR genes association with viral load and CD4 count in HSPs by linear regression (
).
| KIR | Frequency () % | HIV-1 viral load () | | | Median CD4+ T cell count (cells/L) | | |
| 2DL1 | 80.8 | 3.91 | −0.170 | 0.287 | 322 | 0.251 | 0.873 | 2DL2 | 78.2 | 3.94 | −0.250 | 0.115 | 304 | 0.218 | 0.161 | 2DL3 | 72.3 | 3.86 | −0.088 | 0.582 | 331 | −0.074 | 0.638 | 2DL4 | 85.1 | 3.76 | 0.027 | 0.865 | 328 | −0.056 | 0.721 | 2DL5 A | 59.5 | 3.48 | 0.227 | 0.153 | 304 | 0.126 | 0.420 | 2DL5 B | 74.6 | 3.63 | 0.159 | 0.321 | 317 | 0.066 | 0.672 | 2DS1 | 63.8 | 3.27 | 0.404 | 0.009* | 341 | −0.127 | 0.417 | 2DS2 | 85.1 | 3.79 | −0.034 | 0.835 | 318 | 0.072 | 0.647 | 2DS3 | 63.8 | 3.74 | 0.034 | 0.835 | 340 | −0.174 | 0.266 | 2DS4-Nor | 85.1 | 3.55 | 0.163 | 0.307 | 314 | −0.055 | 0.726 | 2DS4-Del | 80.8 | 3.99 | −0.336 | 0.032* | 295 | −0.196 | 0.207 | 2DS5 | 74.4 | 3.59 | 0.188 | 0.238 | 322 | 0.018 | 0.911 | 3DL1 | 78.7 | 3.99 | −0.287 | 0.069 | 342 | −0.185 | 0.235 | 3DL2 | 95.7 | 3.82 | −0.184 | 0.250 | 334 | −0.258 | 0.095 | 3DL3 | 93.6 | 3.79 | −0.074 | 0.644 | 322 | 0.037 | 0.812 | 3DS1 | 72.3 | 3.58 | 0.218 | 0.172 | 327 | −0.033 | 0.835 | 2DP1 | 93.6 | 3.74 | 0.086 | 0.595 | 324 | −0.011 | 0.943 | 3DP1*003 | 82.9 | 3.70 | 0.105 | 0.512 | 333 | 0.116 | 0.458 | 3DP1*001-004 | 27.6 | 3.64 | 0.060 | 0.707 | 299 | 0.082 | 0.602 |
|
|
HSPs: HIV seropositive spouses; OR: odds ratio; CI: confidence interval; values <0.05 are considered statistically significant; : beta value.
|