Research Article
Acute and Subacute Toxicity In Vivo of Thermal-Sprayed Silver Containing Hydroxyapatite Coating in Rat Tibia
Table 2
Laboratory parameters in the subacute phase (4–12 weeks postoperatively).
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Five 14-, 18-, and 22-week-old male Sprague-Dawley rats with no treatment were used as controls for 4, 8, and 12 weeks, respectively. *Mean GOT levels at 4 weeks differed significantly between controls (14-week-old rats) and the HA group (). ** and ***are the mean GOT and LDH levels at 8 weeks that differed significantly between controls (18-week-old rats) and the HA group (). GOT: glutamic-oxaloacetic transaminase; GPT: glutamic-pyruvic transaminase; LDH: lactate dehydrogenase; BUN: blood urea nitrogen. |