Combined Cytolytic Effects of a Vaccinia Virus Encoding a Single Chain Trimer of MHC-I with a Tax-Epitope and Tax-Specific CTLs on HTLV-I-Infected Cells in a Rat Model

<table>Production of IFN-<i>γ</i> by 4O1/C8 that was cocultured with recombinant m8Δ-exposed FPM1V.EFGFP/8R cells. FPM1V.EFGFP/8R cells were exposed to m8Δ/RT1AlSCTax180L, m8Δ/RT1AlSCNLEnv371L, or PBS for 2 hrs at indicated MOI. After extensive wash, the cells were cocultivated with 4O1/C8 for 2 days. Production of IFN-<i>γ</i> in the supernatants of mixed culture was measured by ELISA. The data represent the mean ± SD of triplicate wells. Asterisks indicate statistical significance (<svg height="11.375" id="M22" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>) compared to the mock-infected controls.</table>

BioMed Research International

fig6

Figure 6

Figure 6: Combined Cytolytic Effects of a Vaccinia Virus Encoding a Single Chain Trimer of MHC-I with a Tax-Epitope and Tax-Specific CTLs on HTLV-I-Infected Cells in a Rat Model 

Figure 6 | Combined Cytolytic Effects of a Vaccinia Virus Encoding a Single Chain Trimer of MHC-I with a Tax-Epitope and Tax-Specific CTLs on HTLV-I-Infected Cells in a Rat Model 