Review Article

Clinical Nonlinear Laser Imaging of Human Skin: A Review

Figure 5

SAAID analysis of dermis after laser resurfacing. (a) SAAID images of human dermis at 80 μm, 130 μm, and 180 μm from skin surface before and after microablative fractional laser resurfacing treatment. On the left, representative SAAID images of Group I (age < 35 years) taken before (left column) and 40 days after (right column) treatment. In the middle, representative SAAID images of Group II (35 years < age < 60 years) taken before (left column) and 40 days after (right column) treatment. On the right, representative SAAID images of Group III (age > 60 years) taken before (left column) and 40 days after (right column) treatment. Scale bars: 40 μm. Color-coded scales for SAAID are plotted beneath each of the three groups of figures. SAAID score versus depth of recording for (b) Group I before (black) and after (red) treatment; (c) Group II before (black) and after (red) treatment; (d) Group III before (black) and after (red) treatment. Data are averaged on all the acquired data sets. The error bars correspond to the standard deviation of measured data. The SAAID mean values before and after treatment were found to be statistically different (indicated with *) or not statistically different (no *) at the 0.05 level after a two-sample statistical -test (). Figure derived from [38].
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