Adalimumab Ameliorates Abdominal Aorta Cross Clamping Which Induced Liver Injury in Rats

Table 1

All the biochemical results of three groups.

	Control; (mean ± sd)	I/R; (mean ± sd)	I/R + ADA; (mean ± sd)
ALT (IU/L)	41.1±11.7	59.2±17.5^F	51.4±8.8
AST (IU/L)	23.3±7.5	65.3±11.5^∗,¶	46.7±8.5^∗
Creatinine (mg/dL)	0.4±0.05	0.5±0.05	0.5±0.07
Urea (mg/dL)	39.8±4.6	22.2±9.3^∗,W	42.0±13.8
TNF-𝛼 (pg/mg protein)	345.5±53.3	430.8±70.1^X,𝛼	338.0±71.6
NO (μmol/g protein)	6.5±1.5	8.0±1.1^F,†	6.3±1.2

ADA: adalimumab; I/R: ischemia/reperfusion; TNF-𝛼: tumor necrosis factor-alpha; NO: nitric oxide.
For ALT: ^F𝑃=0.010 versus control group.
For AST: ^∗𝑃<0.001 versus control group; ^¶𝑃=0.003 versus I/R + ADA group.
For Urea: ^∗𝑃<0.001 versus control group; ^W𝑃=0.002 versus I/R + ADA group.
For TNF-α: ^X𝑃=0.008 versus control group; ^𝛼𝑃=0.006 versus I/R + ADA group.
For NO: ^F𝑃=0.010 versus control group; ^†𝑃=0.008 versus I/R + ADA group.