A Large French Case-Control Study Emphasizes the Role of Rare Mc1R Variants in Melanoma Risk

Table 3

Multivariate analysis.

(a) R variants

	OR [95% CI]	P value^a
Hair colour	0.88 [0.69–1.12]	0.292
Eye colour	2.30 [1.63–3.26]	𝟐.𝟔𝟒𝐄−𝟎𝟔
Skin type	1.64 [1.17–2.3]	0.004
Nevus count	1.39 [0.97–1.98]	0.07
R variants	2.22 [1.66–2.97]	𝟔.𝟎𝟎𝐄−𝟎𝟖

(b) r variants

	OR [95% CI]	P value^a
Hair colour	0.98 [0.74–1.29]	0.88
Eye colour	1.93 [1.45–2.57]	𝟏.𝟐𝟎𝐄−𝟎𝟔
Skin type	1.96 [1.49–2.57]	𝟕.𝟑𝟑𝐄−𝟎𝟔
Nevus count	1.6 [1.18–2.15]	0.002
r variants	1.26 [1.04–1.52]	0.018

aP value was calculated by logistic regression.
R: red hair colour variant; r: nonred hair colour variant.
Statistically significant results are shown in bold.