Review Article
The Impact of Simulated and Real Microgravity on Bone Cells and Mesenchymal Stem Cells
Table 1
Comparative methods of 3D cell culture systems using simulated
.
| Device | Working principle |
| Free fall machine | FFM | Free fall for 800 ms, “bounce” of 20 g for 50 ms |
| Levitating magnets | LM | A high gradient magnetic field prevents sedimentation |
| 2D-clinostat | | Rotation along one axis |
| Random positioning machine | RPM | Two frames with randomized movement |
| Rotating wall vessel | RWV | Constant rotation prevents cells from settling |
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