Prolonged Hypocalcemic Effect by Pulmonary Delivery of Calcitonin Loaded Poly(Methyl Vinyl Ether Maleic Acid) Bioadhesive Nanoparticles

Table 4

Correlation coefficients of different kinetic models obtained by curve fitting method to sCT release data from different nanoparticles.

Formulation code	First-order	Zero-order	Higuchi model
𝑅1000𝐼Fe𝐶5	0.921	0.986	0.952
𝑅400𝐼Fe𝐶5	0.936	0.986	0.952
𝑅400𝐼Zn𝐶20	0.956	0.987	0.959
𝑅1000𝐼Zn𝐶5	0.935	0.983	0.967
𝑅1000𝐼Zn𝐶20	0.967	0.985	0.946
𝑅400𝐼Zn𝐶5	0.969	0.986	0.956
𝑅1000𝐼Fe𝐶20	0.925	0.985	0.950
𝑅400𝐼Fe𝐶20	0.955	0.986	0.958