Prolonged Hypocalcemic Effect by Pulmonary Delivery of Calcitonin Loaded Poly(Methyl Vinyl Ether Maleic Acid) Bioadhesive Nanoparticles

Table 5

Comparison of the Design Expert predicted and actual values of responses studied in sCT loaded P(MVEMA) nanoparticles.

Response	Particle size; (nm)	Zeta potential; (mV)	Drug loading efficiency; (%)	Release; efficiency; (RE24 %)	Mucoadhesive efficiency; (%)
Predicted	188.3	−21.0	92.7	45.1	90.67
Actual	196.1±6.9	−19.7±1.7	92.2±2.5	49.5±2	90.66±0.04
Error %	4.1	6.2	0.5	9.9	0.01