Hepatoprotective Effect of Superfine Particles of Herbal Medicine against CCl₄-Induced Acute Liver Damage in Rats

Table 1

Effects of SPRT on bax and caspase-3 expression in rat liver treated with CCl₄.

Group	Concentration	Mean density	Mean density
		Bax	Caspase-3
Control	—	0	0
Model	—	0.0683 ± 0.0161^##	0.0536 ± 0.0188^##
Bifendate	200 mg/kg	0.0539 ± 0.0192	0.0394 ± 0.0154
SPRT-1	0.3 g/kg	0.0624 ± 0.0170	0.0388 ± 0.0203
SPRT-2	0.6 g/kg	0.0450 ± 0.0179*	0.0358 ± 0.0148*
SPRT-3	1.2 g/kg	0.0359 ± 0.0245**	0.0311 ± 0.0064*

Data are expressed as mean ± SD (n = 10). ^##P < 0.01 compared to normal controls; **P < 0.01, *P < 0.05 compared to disease model group.