Structural Basis of Binding and Rationale for the Potent Urease Inhibitory Activity of Biscoumarins

Figure 6

Another view showing the interaction of compounds 7 and 3 with urease (Bacillus pasteurii) from another angle. Ligand 7 is penetrated in to the active site but ligand 3 is unable to reach probably because of its shape, the phenyl ring of the ligand 7 is symmetrically placed inside the active site.