The K–Cl Cotransporter KCC3 as an Independent Prognostic Factor in Human Esophageal Squamous Cell Carcinoma
Figure 3
Survival curve of patients after curative resection for esophageal squamous cell carcinoma (ESCC) according to the expression of KCC3. (a) Patients were classified into two groups: low grade expression of KCC3 () and high grade expression of KCC3 () in the main tumor (MT). (b) Patients were classified into two groups: the low grade expression of KCC3 () and high grade expression of KCC3 () in the cancer nest (CN). (c) Patients were classified into two groups based on comparisons of the KCC3 score: CC ≤ MT () and CN > MT () in the cancer nest (CN). (d) Patients were classified into two groups based on the expression of KCC3 in the invasive front of the tumor: negative () and positive (). (e) Patients were classified into two groups: patients with CN > MT and invasive front positive () and others (). ∗: log-rank test.
