Research Article

Chromatographic Fingerprint Analysis and Effects of the Medicinal Plant Species Mitracarpus frigidus on Adult Schistosoma mansoni Worms

Figure 2

Effects of Mitracarpus frigidus methanolic extract on hepatic granuloma. At 60 days of infection, the hepatic tissues were collected and used for morphological study of the granulomatous area. All granulomas containing a central viable egg were measured and photographed. In (a) general aspects of the hepatic granulomas obtained from infected and untreated animals; (b) the infiltrate around the granuloma in treated animals with a single dose (200 mg/kg) of praziquantel is shown. In ((c), 100 mg/Kg) and ((d), 300 mg/kg) the granulomas from infected and treated animals after 20 days with different doses of the M. frigidus extract, showing that there are no changes in their structure and granulomatous infiltrate.
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(a)
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(b)
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(c)
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(d)