Chromatographic Fingerprint Analysis and Effects of the Medicinal Plant Species Mitracarpus frigidus on Adult Schistosoma mansoni Worms

Table 1

Effects of Mitracarpus frigidus methanolic (MFM) extract treatment on body weight, relative organ weights, and granuloma formation, after 60 days of infection.

	Non-infected groups				Infected groups
	Group A	Group B	Group C	Group D	Group E	Group F	Group G	Group H
	Negative control	Praziquantel	MFM	MFM	Negative control	Praziquantel	MFM	MFM
		200 mg/kg	100 mg/kg	300 mg/kg		200 mg/kg	100 mg/kg	300 mg/kg
Body weight (g)	26.5±0.5	24.5±0.7	24.8±0.9	25.3±0.6	28.0±0.5	27.9±0.5	26.5±0.5	24.5±0.7
Relative liver weights	4.9±0.2	5.4±0.2	5.4±0.1	5.4±0.2	12.8±0.7	12.0±0.4	4.9±0.2	5.4±0.2
Relative spleen weights	0.3±0.04	0.3±0.04	0.4±0.03	0.5±0.09	3.4±0.2	2.8±0.3	0.3±0.04	0.3±0.04
Number of granulomas	—	—	—	—	62.2±1.6	45.1±3.1^a	—	—
Mean granuloma diameter (𝜇m)	—	—	—	—	7.4±0.3	8.8±0.1^a	—	—

The values shown are mean ± SEM (𝑛=10). ^aStatistically different from the infected, negative control group (E) (ANOVA followed by Bonferroni, P < 0.05).