New SPECT and PET Radiopharmaceuticals for Imaging Cardiovascular Disease
Figure 1
Schematic representation of cardiac PET and SPECT radiotracers uptake in relation to myocardial perfusion. 15O–H2O demonstrates close to linear uptake whereas the initial linear extraction of technetium-99m labeled compounds plateau at approximately 2 mL/min/g. PET radiotracers and fall between and the -SPECT radiotracers, whereas -teboroxime demonstrates superior extraction at high flow rates. 18F-flurpiridaz rivals 15O–H2O with closer to linear extraction [11].
