Review Article

New SPECT and PET Radiopharmaceuticals for Imaging Cardiovascular Disease

Table 8

PET Radiotracers for Imaging Atherosclerotic Plaques.

18F-NaFSodium 18F-Fluoride (18F-NaF)
(i) capacity to identify ruptured or high-risk coronary atherosclerotic plaques (Figure 9)
(ii) at risk plaques have positive remodelling, microCa2+ and large necrotic core
(iii) fluoride ion (18Fāˆ’) mimics hydroxyl ion and is deposited in nucleating hydroxyapatite crystals of calcified endothelium