New SPECT and PET Radiopharmaceuticals for Imaging Cardiovascular Disease
Table 8
PET Radiotracers for Imaging Atherosclerotic Plaques.
18F-NaF
Sodium 18F-Fluoride (18F-NaF) (i) capacity to identify ruptured or high-risk coronary atherosclerotic plaques (Figure 9) (ii) at risk plaques have positive remodelling, microCa2+ and large necrotic core (iii) fluoride ion (18Fā) mimics hydroxyl ion and is deposited in nucleating hydroxyapatite crystals of calcified endothelium