Geometric Analysis of Alloreactive HLA α-Helices

Figure 1

Molecular structure of MHC class I. Three-dimensional representation of secondary structural elements of. (a) HLA-B^∗44:05 (grey), ABCD3 peptide (orange), and 𝛽₂-microglobulin (ice blue). (b) HLA-B^∗44:05 (grey), ABCD3 peptide (orange), 𝛽₂-microglobulin (ice blue), and LC13 T cell receptor (dark blue and red). PDB ID: 3KPS.

(a)

(b)