Intrinsic Functional Connectivity Networks in Healthy Elderly Subjects: A Multiparametric Approach with Structural Connectivity Analysis

Figure 6

Orthogonal slices of ten well-matched pairs of ICNs ((a)–(j)) in the stereotaxic MNI space for a representative single subject (male, 60 years) overlaid on the individual MPRAGE (left columns) and for the complete healthy subject group (𝑁=12) displayed on their averaged MPRAGE (right columns). Connectivity strengths of brain maps are depicted in hot colors, thresholded for |𝑧(𝑟)|>0.4 corresponding to 𝑃<0.0000001. (a) The default mode ICN (DMN). ((b), (c)) The left and right frontoparietal control (FPC) ICNs. (d) The motor (MOT) ICN. (e) The visuospatial (VIS) ICN. (f) The dorsal attention (DA) system. (g) The ventral attention (VA) ICN. (h) The basal ganglia thalamic (BT) ICN. (i) The brainstem (BS) ICN. (j) The cerebellar (CB) ICN.

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