Evaluation of Buspirone on Streptozotocin Induced Type 1 Diabetes and Its Associated Complications

Table 1

Effect of Buspirone on body weight, food and water intake, glucose levels and renal parameters.

Parameters	CON	COB	DIC	DIB
Body weight (gm)	217.5±4.95	204.17±4.36	209.37±8.78^∗	220±5.77^#
Food intake (gm)	83.33±4.21	78.33±3.07	140±12.11^∗	60±9.31^#
Water intake (mL)	116.67±8.82	108.33±10.77	386.67±9.89^∗	91.67±6.1^#
Glucose (mg/dL)	75.08±3.90	85.31±4.85	317.14±8.98^∗	210.25±8.65^#
Creatinine (mg/dL)	0.58±0.03	0.6±0.02	0.85±0.06^∗	0.7±0.02^#
Urea (mg/dL)	45.85±3.73	47.31±3.07	65.61±1.29^∗	51.22±2.09^#

∗Significantly different from normal control (𝑃<0.05).
#Significantly different from diabetic control (𝑃<0.05).
Values are expressed as mean ± SEM of 6 experiments.
CON: normal control, COB: control treated with buspirone, DIC: diabetic control, and DIB: diabetic treated with buspirone.