Research Article

Perinatal Nitric Oxide Therapy Prevents Adverse Effects of Perinatal Hypoxia on the Adult Pulmonary Circulation

Figure 3

Western blotting analysis of eNOS protein expression in pulmonary arteries. (a) Western blotting analysis of eNOS protein relative content was performed in pulmonary arteries extracts ( pools of 10 PA) of adult females born in normoxia (Ctr) or in hypoxia (PH). These data were previously published in [13]. Significant difference between Ctr and PH groups ( using unpaired -test). (b) Relative eNOS protein content was analyzed in pulmonary arteries extracts of adult mice born in normoxia (Ctr) or exposed simultaneously to hypoxia and iNO in the perinatal period (PH + NO) ( mice). Results are expressed as mean ± SEM of the relative eNOS protein content after normalization by β-actin protein content.
949361.fig.003a
(a)
949361.fig.003b
(b)