Biochemical and Functional Characterization of Parawixia bistriata Spider Venom with Potential Proteolytic and Larvicidal Activities

Table 3

Frequency of nucleoids with comet after treatment of human lymphocytes with Parawixia bistriata spider venom.

Treatments (μg/mL)	Damaged nucleoids (%)	A.U.
^aNegative control
—	22	22*
^bPositive control
6	39.75	134.5^#
P. bistriata
2.5	38	49^#∗
5	40.3	52.9^#∗
7.5	57.1	76.9^#∗
10	62.5	83.3^#∗
15	70.6	97.7^#∗
30	80.5	115.3^#∗
60	83	117.1^#∗
120	80.6	113.6^#∗

aNegative control: culture of untreated cells, bpositive control: doxorubicin (6 𝜇g/mL). A.U.: arbitrary units (0–400) calculated according to [7]. #Statistically different from the negative control (𝑃<0.05). ∗Statistically different from the positive control (𝑃<0.05).