Ultrasound-Mediated Local Drug and Gene Delivery Using Nanocarriers
Figure 1
Schematic overview of various nano/microbubbles used for ultrasound-mediated drug/gene delivery. (a) The drug-loaded nano/microbubbles releasing drugs upon insonation. (b) Nanodroplets extravasate because of EPR and come into being microbubbles after a phase transition. (c) Nanosized lipospheres which can be activated by ultrasound in tumor tissues. (d) Bubbles associated with targeting moiety can adhere to the target molecules in tissue which express epitopes [17].
