Novel Bifunctional Single-Chain Variable Antibody Fragments to Enhance Virolysis by Complement: Generation and Proof-of-Concept
Figure 3
Schematic overview of 48scFVSCR1920. Expression vector pPICZαB (a) for expression in Pichia provides a leader sequence for secretion which is cleaved prior to release of scFv. The vector contains poly-Histidine- (“H”) and Strep-Tag (“S”). Vector and final construct (b) are displayed schematically with SCR-modules.
