Inhibition of Ceramide De Novo Synthesis with Myriocin Affects Lipid Metabolism in the Liver of Rats with Streptozotocin-Induced Type 1 Diabetes
Figure 2
Effect of myriocin treatment (for 7 days) and streptozotocin-induced diabetes (for 7 days) on sphingomyelin (a), sphingosine (b), and sphingosine-1-phosphate (c) contents in liver homogenates. C: control group. M: group treated with myriocin. D: streptozotocin-induced diabetes group. D + M: treptozotocin-induced group treated with myriocin. Results are based on 8 independent preparations for each experimental treatment (means ± SE). * compared with C group. † compared with D group.