Arrabidaea chica Hexanic Extract Induces Mitochondrion Damage and Peptidase Inhibition on Leishmania spp.
Figure 4
Nitric oxide synthesis by Leishmania-infected macrophages treated with the B2 fraction. After 48 hours treatment with the B2 fraction the supernatant from L. amazonensis- and L. infantum-infected macrophages was collected and the nitrite content determined through Griess reaction. Each point represents the mean ± S.E. of 2 independent experiments performed in triplicate. MIC and subMIC values for L. amazonensis and L. infantum were 37.2 and 18.6 μg/mL and 18.6 and 9.3 μg/mL, respectively. Asterisks indicate that treated parasites were statistically different () from control parasites.
