Matrilin-2 Is a Widely Distributed Extracellular Matrix Protein and a Potential Biomarker in the Early Stage of Osteoarthritis in Articular Cartilage
Figure 4
Comparisons the matrilin-2 mRNA and protein expression between newborn and adult mouse knee. Newborn and adult mouse knee were investigated by quantitative real-time RT-PCR (a) and Western blot (b). There is plenty of matrilin-2 mRNA in newborn mouse knee; the level of mRNA is significantly decreased () in the adult mouse knee (a). By Western blot (b), consistent with quantitative real-time RT-PCR (a) and immunohistochemistry results (Figure 3), the protein level of matrilin-2 is significantly decreased in the adult mouse knee (b).
