Prevalence of Human Papillomavirus Variants and Genetic Diversity in the L1 Gene and Long Control Region of HPV16, HPV31, and HPV58 Found in North-East Brazil

Table 4

HPV16 LCR sequence variations with regard to the reference sequence K02718.1. The table also shows the putative transcriptional factor binding sites in the nucleotide altered.

Genome position	Nucleotide variation	Number of isolates	Transcriptional factor
7175	A/C	1/23	C/EBPbeta
7194	G/T	10/23
7229	A/C	1/23	C/EBPbeta
7234	A/C	10/23
7258	G/A	1/23	YY1
7281	G/T	1/23
7316	A/C	1/23	YY1, AP-1
7340	A/T	7/23	C/EBPbeta
7360	A/G	1/23
7361	G/C	1/23
7395	C/T	7/23	C/EBPbeta
7434	Ins C	23/23	NF-1, YY1
7436	C/G	23/23	YY1
7441	T/G	1/23	YY1
7485	A/C	9/23	NF1
7490	G/A	9/23
7521	G/A	10/23	YY1
7670	C/T	9/23
7690	C/A	9/23	E2
7730	A/C	8/23	Oct-1
7730	A/T	1/23	Oct-1
7747	T/G	7/23	C/EBPbeta
7768	C/T	9/23	NF-1
7790	C/T	1/23	YY1
7790	C/T	9/23	YY1
7838	G/T	2/23	C/EBPbeta
7869	Del A	23/23	E2
7874	G/A	1/23	NF-1
7881	C/A	1/23	C/EBPbeta
7891	C/G	7/23	C/EBPbeta