Identification of Glioblastoma Phosphotyrosine-Containing Proteins with Two-Dimensional Western Blotting and Tandem Mass Spectrometry

Figure 7

Experimental data-based diagram that rationalizes phosphotyrosine-containing proteins in the glioma biological system. The orange frame means identified phosphotyrosine-containing proteins. ANXA5, annexin A5; PLXD1, plexin-D1; TRAP1, TNFR-associated protein 1 (heat shock protein 75 kDa, mitochondrial); PRP8, pre-mRNA-processing-splicing factor 8; ACTB, actin, cytoplasmic 1; ZN569, zinc finger protein 569; GFAP, glial fibrillary acidic protein; HEXA, beta-hexosaminidase subunit alpha; ENOA, alpha-enolase; LDHB, L-lactate dehydrogenase B chain; 14-3-3, 14-3-3 protein; HSP90A, heat shock protein HSP 90-alpha; TBAIA, tubulin alpha-1A chain; CE192, centrosomal protein of 192 kDa; ACTBL, beta-actin-like protein 2; TBA8, tubulin alpha-8 chain; ARAP1, Arf-GAP with Rho-GAP domain, ANK repeat, and PH domain-containing protein 1; HXA1, homeobox protein Hox-A1; APOA1, apolipoprotein A-I; and HSP90B, heat shock protein HSP 90-beta.