Review Article

Recent Advances on Pathophysiology, Diagnostic and Therapeutic Insights in Cardiac Dysfunction Induced by Antineoplastic Drugs

Table 1

Current insights in prevention, monitoring and treatment of cardiac dysfunction induced by anticancer drugs. Modified from [102].

PreventionMonitoringTreatment

Alternative anticancer strategies
Reduced chemotherapeutic dose
Liposomal formulations
Less toxic alternatives (epirubicin, lapatinib)
Better patients selection
Age
Cardiac risk
Cardiac function
Use of cardioprotective drugs
β-blockers
ACE inhibitors
ARBs
Dexrazoxane
Statins
Imaging
Assess the best modality
Assess the best frequency
Biomarkers
BNP
Troponins
Novel markers (MPO?)
Hold or stop antineoplastic treatments
Start HF therapies