Magnolia officinalis Extract Contains Potent Inhibitors against PTP1B and Attenuates Hyperglycemia in db/db Mice

Table 1

Selectivity of ME towards a panel of PTPs.

PTPs	IC50 (μg/mL); ME
PTP1B	55.96 ± 1.14
SHP1	501.94 ± 11.55
SHP2	521.56 ± 15.76
TCPTP	395.59 ± 9.76
HePTP	677.88 ± 13.25

IC₅₀ values of ME against PTPs including PTP1B, SHP1, SHP2, TCPTP, and HePTP were calculated. Data were expressed as mean ± standard error ().