Initial In Vivo Evaluation of a Novel Left Ventricular Assist Device

Table 1

Mean preoperative and postoperative hematologic and biochemical data.

	Preoperative	Day 1	Day 5	Day 10	Day 20	Day 30
Hematologic data (mean ± SD)
White blood cells ×10^9/L	10.3 ± 1.6	29.9 ± 11.3	22.3 ± 8.7	15.6 ± 4.6	10.3 ± 1.6	9.6 ± 1.3
Red blood cells ×10^12/L	7.9 ± 1.6	5.7 ± 1.1	6.2 ± 0.8	7.1 ± 0.7	7.7 ± 1.1	8.1 ± 0.3
Hemoglobin, g/L	107 ± 12.6	96 ± 7.7	91 ± 6.8	68 ± 5.0	91 ± 9.3	97 ± 8.2
Hematocrit, %	31.14 ± 1.05	25.56 ± 2.03	25.34 ± 2.17	22.97 ± 1.45	21.86 ± 1.12	21.5 ± 2.13
Prothrombin time, sec	13.2 ± 0.7	15.4 ± 1.1	20.6 ± 5.12	17.2 ± 3.14	14.6 ± 1.45	14.7 ± 1.12
International normalized ratio	1.22 ± 0.08	2.3 ± 1.34	3.14 ± 0.89	1.46 ± 0.52	1.23 ± 0.37	1.24 ± 0.18
Partial thromboplastin time, sec	32.35 ± 5.12	47.44 ± 4.23	57.21 ± 5.18	50.3 ± 4.65	44.92 ± 3.36	39.55 ± 4.63
Fibrinogen, mg/dL	410.1 ± 52.2	407.5 ± 45.3	387.1 ± 38.9	313.7 ± 45.2	279.7 ± 36.7	222.7 ± 39.8
FHB, g/L	0.039 ± 0.021	0.055 ± 0.014	0.093 ± 0.035	0.066 ± 0.024	0.065 ± 0.018	0.068 ± 0.026
Biochemical data (mean ± SD)
SGOT (ALT), U/L	16.3 ± 2.1	40.9 ± 5.2	28.5 ± 3.3	17 ± 2.9	14 ± 1.8	15.7 ± 2.3
Total bilirubin, Umol/L	2.1 ± 0.3	2.4 ± 0.7	3.9 ± 1.1	2.7 ± 0.8	2.4 ± 0.6	2.1 ± 0.8
Albumin, g/dL	2.6 ± 0.2	2.1 ± 0.9	2.2 ± 0.4	2.0 ± 0.5	2.3 ± 0.6	2.4 ± 0.3
AST, U/L	124.8 ± 89.6	259.4 ± 91.2	170.8 ± 75.6	106.1 ± 57.6	103.5 ± 45.9	102.3 ± 46.8
Glutamyl endopeptidase, U/L	81.3 ± 35.7	65.7 ± 33.6	54.3 ± 22.5	60.7 ± 17.9	64.4 ± 22.1	61.1 ± 24.5
Serum urea nitrogen, mmol/L	5.42 ± 1.32	10.64 ± 2.89	7.36 ± 1.25	6.41 ± 1.10	5.72 ± 0.89	5.33 ± 0.75
Creatinine, Umol/L	76.6 ± 9.32	67.4 ± 10.23	69.1 ± 11.32	70.6 ± 12.69	73.2 ± 11.85	66.6 ± 13.10
Glucose, Umol/L	3.16 ± 0.28	3.65 ± 0.54	3.80 ± 0.32	3.45 ± 0.49	2.54 ± 0.36	3.59 ± 0.41

SGOT (ALT): serum glutamic-oxaloacetic transaminase (alanine aminotransferase); AST: aspartate aminotransferase.