Liver-Specific Inactivation of the Proprotein Convertase FURIN Leads to Increased Hepatocellular Carcinoma Growth

<div>Expression of AFP is not altered upon genetic ablation of<i> Furin</i> in the liver. The expression of AFP was increased in the liver tumors of 13- and 19-week-old mice compared to that in normal livers as assessed by western blot analysis. However, the expression of AFP was similar in tumors of<i> Furin</i> knockout and<i> Furin</i> wild type mice.</div>

BioMed Research International

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Figure 5

Figure 5: Liver-Specific Inactivation of the Proprotein Convertase FURIN Leads to Increased Hepatocellular Carcinoma Growth 