Clinical Study

The Association between Cerebral White Matter Lesions and Plasma Omega-3 to Omega-6 Polyunsaturated Fatty Acids Ratio to Cognitive Impairment Development

Table 1

Factors associated with the progression of deep and subcortical white matter hyperintensity (DSWMH) grades using median values of PUFA.

FactorsDSWMH
EstimateSEChi-square value

Age −0.1217 0.0176 47.59 <0.0001
Female sex −0.9703 0.2650 13.41 0.0003
Hypertension −0.8629 0.2567 11.30 0.0008
Dyslipidemia −0.1569 0.2447 0.41 0.5215
Diabetes −0.3323 0.3353 0.98 0.3216
Smoking −0.1907 0.2697 0.50 0.4795
ICA plaque −0.9129 0.2608 12.25 0.0005
EPA/AA < 0.38 −1.4752 0.2900 25.88 <0.0001
DHA/AA < 0.84 −0.2798 0.2772 1.02 0.3128