Clinical Study

The Association between Cerebral White Matter Lesions and Plasma Omega-3 to Omega-6 Polyunsaturated Fatty Acids Ratio to Cognitive Impairment Development

Table 2

Factors associated with the progression of periventricular hyperintensity (PVH) grades using median values of PUFA.

Factors PVH
Estimate SE Chi-square value

Age −0.1534 0.0194 62.48 <0.0001
Female sex −0.8844 0.2775 10.16 0.0014
Hypertension −0.6569 0.2730 5.79 0.0161
Dyslipidemia −0.1749 0.2612 0.45 0.5032
Diabetes −0.5092 0.3536 2.07 0.1498
Smoking −0.5132 0.2859 3.22 0.0726
ICA plaque −0.5532 0.2748 4.05 0.0441
EPA/AA < 0.38 −1.1522 0.3072 14.06 0.0002
DHA/AA < 0.84 −0.4061 0.2994 1.84 0.1750